A Combinatorial Library of Lipid Nanoparticles for Cell Type‐Specific mRNA Delivery (Adv. Sci. 19/2023)

نویسندگان

چکیده

Lipid Nanoparticles In article number 2301929, Dan Peer and colleagues developed novel ionizable lipids for improved delivery of mRNA payloads. Rational lipid design together with in vivo screening identified lipid-based nanoparticles (LNPs) enhanced cell trophism. This study suggests that a structural combination tail linker can drive trophism LNPs vivo.

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ژورنال

عنوان ژورنال: Advanced Science

سال: 2023

ISSN: ['2198-3844']

DOI: https://doi.org/10.1002/advs.202370118